3G04
Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HUMAN THYROID STIMULATING AUTOANTIBODY M22 LIGHT CHAIN | polymer | 216 | 23043.4 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | HUMAN THYROID STIMULATING AUTOANTIBODY M22 HEAVY CHAIN | polymer | 228 | 24487.4 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Thyrotropin receptor | polymer | 239 | 26943.8 | 1 | UniProt (P16473) Pfam (PF13306) | Homo sapiens (human) | Thyroid-stimulating hormone receptor, TSH-R |
| 4 | D, G, H, I, J... (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 5 | E, F, L, M, N (A, C) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 6 | O, P, Q (A, B, C) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74474.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1654.3 | |
| All* | Total formula weight | 76129.0 |
