3FGM

Crystal structure of L44F/C83T/C117V/F132W mutant of Human acidic fibroblast growth factor

Summary for 3FGM

Entry DOI	10.2210/pdb3fgm/pdb
Related	1JQZ 3FJ8 3FJ9 3FJA 3FJB 3FJC 3FJD 3FJE 3FJF 3FJH 3FJI 3FJJ 3FJK
Descriptor	Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID, ... (4 entities in total)
Functional Keywords	beta-trefoil, acetylation, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, hormone
Biological source	Homo sapiens (human)
Cellular location	Secreted: P05230
Total number of polymer chains	2
Total formula weight	33741.63
Authors	Blaber, M.,Lee, J. (deposition date: 2008-12-06, release date: 2009-10-06, Last modification date: 2023-09-06)
Primary citation	Lee, J.,Blaber, M. The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. J.Mol.Biol., 393:113-127, 2009 Cited by PubMed: 19695265 DOI: 10.1016/j.jmb.2009.08.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation