3FGM
Crystal structure of L44F/C83T/C117V/F132W mutant of Human acidic fibroblast growth factor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Heparin-binding growth factor 1 | polymer | 146 | 16753.7 | 2 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (human) | HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta |
2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
3 | A, B | FORMIC ACID | non-polymer | 46.0 | 3 | Chemie (FMT) | |||
4 | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
PDB | External Database | Details |
---|---|---|
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
Phe 44 | Leu 59 | engineered mutation |
Thr 83 | Cys 98 | engineered mutation |
Val 117 | Cys 132 | engineered mutation |
Trp 132 | Phe 147 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33507.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 234.1 | |
All* | Total formula weight | 33741.6 |