3EX6
D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct
Summary for 3EX6
| Entry DOI | 10.2210/pdb3ex6/pdb |
| Related | 3EWU 3EWW 3EWX 3EWY 3EWZ 3EX0 3EX1 3EX2 3EX3 3EX4 3EX5 |
| Descriptor | Orotidine-5'-phosphate decarboxylase, GLYCEROL, SULFATE ION, ... (6 entities in total) |
| Functional Keywords | decarboxylase, tim barrel, unusual catalysis, disease mutation, glycosyltransferase, lyase, multifunctional enzyme, pyrimidine biosynthesis, transferase |
| Biological source | Homo sapiens |
| Total number of polymer chains | 2 |
| Total formula weight | 57241.37 |
| Authors | Heinrich, D.,Diederichsen, U.,Rudolph, M. (deposition date: 2008-10-16, release date: 2009-04-07, Last modification date: 2023-12-27) |
| Primary citation | Heinrich, D.,Diederichsen, U.,Rudolph, M.G. Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase Chemistry, 15:6619-6625, 2009 Cited by PubMed: 19472232DOI: 10.1002/chem.200900397 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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