3EX3
human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct
Summary for 3EX3
| Entry DOI | 10.2210/pdb3ex3/pdb |
| Related | 3EWU 3EWW 3EWX 3EWY 3EWZ 3EX0 3EX1 3EX2 3EX4 3EX5 3EX6 |
| Descriptor | Orotidine-5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | decarboxylase, tim barrel, unusual catalysis, disease mutation, glycosyltransferase, lyase, multifunctional enzyme, pyrimidine biosynthesis, transferase |
| Biological source | Homo sapiens |
| Total number of polymer chains | 2 |
| Total formula weight | 57339.94 |
| Authors | Heinrich, D.,Diederichsen, U.,Rudolph, M. (deposition date: 2008-10-16, release date: 2009-04-07, Last modification date: 2023-12-27) |
| Primary citation | Heinrich, D.,Diederichsen, U.,Rudolph, M.G. Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase Chemistry, 15:6619-6625, 2009 Cited by PubMed: 19472232DOI: 10.1002/chem.200900397 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
Download full validation report
