3EX6
D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Orotidine-5'-phosphate decarboxylase | polymer | 260 | 28298.8 | 2 | UniProt (P11172) Pfam (PF00215) In PDB | Homo sapiens | OMPdecase |
2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | B | URIDINE-5'-MONOPHOSPHATE | non-polymer | 324.2 | 1 | Chemie (U5P) | |||
6 | water | water | 18.0 | 506 | Chemie (HOH) |
Sequence modifications
A, B: 224 - 480 (UniProt: P11172)
PDB | External Database | Details |
---|---|---|
Gly 221 | - | expression tag |
Ala 222 | - | expression tag |
Met 223 | - | expression tag |
Asn 312 | Asp 312 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56597.5 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 643.9 | |
All* | Total formula weight | 57241.4 |