3ETQ

X-ray structure of cysteine-free fragment of mHCN2 C-terminal region from amino acids 443-630 including C508N, C584S, and C601S mutations

Summary for 3ETQ

Entry DOI	10.2210/pdb3etq/pdb
Related	1Q3E 1Q43 1Q5O 2Q0A 3BPZ
Descriptor	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
Functional Keywords	hcn, ion channel, camp, cyclic nucleotide binding domain, beta roll, c-linker, camp-binding, glycoprotein, ion transport, ionic channel, membrane, nucleotide-binding, phosphoprotein, potassium, potassium channel, potassium transport, sodium, sodium channel, sodium transport, transmembrane, transport, voltage-gated channel, transport protein
Biological source	Mus musculus (mouse)
Cellular location	Cell membrane ; Multi-pass membrane protein : O88703
Total number of polymer chains	2
Total formula weight	48400.88
Authors	Flynn, G.E. (deposition date: 2008-10-08, release date: 2009-06-23, Last modification date: 2023-09-06)
Primary citation	Taraska, J.W.,Puljung, M.C.,Olivier, N.B.,Flynn, G.E.,Zagotta, W.N. Mapping the structure and conformational movements of proteins with transition metal ion FRET. Nat.Methods, 6:532-537, 2009 Cited by PubMed: 19525958 DOI: 10.1038/nmeth.1341 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation