3EHT
Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF
Summary for 3EHT
Entry DOI | 10.2210/pdb3eht/pdb |
Related | 3EHS 3EHU |
Related PRD ID | PRD_900001 |
Descriptor | FUSION PROTEIN OF CRFR1 EXTRACELLULAR DOMAIN AND MBP, Corticoliberin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (3 entities in total) |
Functional Keywords | g protein-coupled receptor, corticotropin releasing factor, scr fold, mbp fusion, extracellular domain, sugar transport, transport, cell membrane, glycoprotein, membrane, phosphoprotein, receptor, transducer, transmembrane, amidation, cleavage on pair of basic residues, hormone, secreted, membrane protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 54624.46 |
Authors | Pioszak, A.A.,Xu, H.E. (deposition date: 2008-09-14, release date: 2008-09-30, Last modification date: 2023-08-30) |
Primary citation | Pioszak, A.A.,Parker, N.R.,Suino-Powell, K.,Xu, H.E. Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1. J.Biol.Chem., 283:32900-32912, 2008 Cited by PubMed: 18801728DOI: 10.1074/jbc.M805749200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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