3E1Z
Crystal structure of the parasite protesase inhibitor chagasin in complex with papain
Summary for 3E1Z
Entry DOI | 10.2210/pdb3e1z/pdb |
Related | 1KHQ 1ME3 2NQD 2OUL 3CBJ 3CBK |
Descriptor | Chagasin, Papain, ZINC ION, ... (6 entities in total) |
Functional Keywords | chagasin-papain complex, papain, chagas disease, cysteine proteinases, protein inhibitors, cytoplasmic vesicle, protease inhibitor, thiol protease inhibitor, allergen, hydrolase, protease, thiol protease, zymogen, hydrolase inhibitor-hydrolase complex, hydrolase inhibitor/hydrolase |
Biological source | Trypanosoma cruzi More |
Cellular location | Flagellar pocket: Q966X9 |
Total number of polymer chains | 2 |
Total formula weight | 36092.49 |
Authors | Redzynia, I.,Bujacz, G.,Bujacz, A.,Ljunggren, A.,Abrahamson, M.,Jaskolski, M. (deposition date: 2008-08-05, release date: 2009-01-27, Last modification date: 2023-11-01) |
Primary citation | Redzynia, I.,Ljunggren, A.,Bujacz, A.,Abrahamson, M.,Jaskolski, M.,Bujacz, G. Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases. Febs J., 276:793-806, 2009 Cited by PubMed: 19143838DOI: 10.1111/j.1742-4658.2008.06824.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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