3DZI
Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate intermediate/GTP complex
Summary for 3DZI
Entry DOI | 10.2210/pdb3dzi/pdb |
Related | 3DZF 3DZG 3DZH 3DZJ 3DZK |
Descriptor | ADP-ribosyl cyclase 1, 2-amino-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-9H-purin-6-yl 5-O-phosphono-beta-D-ribofuranoside, ANY 5'-MONOPHOSPHATE NUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | noncovalent intermediate, gtp complex, r5p-gtp adduct, beta sheets, alpha bundle, alternative splicing, diabetes mellitus, glycoprotein, hydrolase, membrane, nad, polymorphism, receptor, signal-anchor, transmembrane |
Biological source | Homo sapiens |
Cellular location | Membrane; Single-pass type II membrane protein: P28907 |
Total number of polymer chains | 2 |
Total formula weight | 62233.35 |
Authors | Liu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q. (deposition date: 2008-07-29, release date: 2008-11-04, Last modification date: 2023-08-30) |
Primary citation | Liu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q. Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38. Chem.Biol., 15:1068-1078, 2008 Cited by PubMed: 18940667DOI: 10.1016/j.chembiol.2008.08.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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