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3DZI

Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate intermediate/GTP complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0061809molecular_functionNAD+ nucleotidase, cyclic ADP-ribose generating
B0061809molecular_functionNAD+ nucleotidase, cyclic ADP-ribose generating
Functional Information from PDB Data
site_idAC1
Number of Residues11
DetailsBINDING SITE FOR RESIDUE GTP B 302
ChainResidue
BARG127
BHOH540
BHOH579
BGLU146
BASP155
BVAL185
BTRP189
BSER193
BTHR221
BN301
BHOH458

site_idAC2
Number of Residues22
DetailsBINDING SITE FOR RESIDUE RGT A 301
ChainResidue
ALEU124
ATRP125
ASER126
AARG127
ALYS129
ALEU145
AGLU146
AASP155
AASP175
ATRP176
AARG177
AVAL185
ATRP189
ASER193
ASER220
ATHR221
APHE222
AGLU226
AHOH303
AHOH340
AHOH386
AHOH426

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: ACT_SITE => ECO:0000305|PubMed:7961800
ChainResidueDetails
ACYS119
ACYS201
BCYS119
BCYS201

site_idSWS_FT_FI2
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
ChainResidueDetails
AASP100
AASP209
BASP100
BASP209

site_idSWS_FT_FI3
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASP164
BASP164

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973
ChainResidueDetails
AASP219
BASP219

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1r16
ChainResidueDetails
AGLU226
AGLU146

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1r16
ChainResidueDetails
BGLU226
BGLU146

226707

PDB entries from 2024-10-30

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