Crystal structure of the active G-protein-coupled receptor opsin in complex with a C-terminal peptide derived from the Galpha subunit of transducin

Summary for 3DQB
DescriptorRhodopsin, 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsprotein, retinal protein, photoreceptor, ligand-free state, chromophore, g-protein coupled receptor, glycoprotein, lipoprotein, palmitate, phosphoprotein, photoreceptor protein, sensory transduction, transducer, transmembrane, vision, signaling protein, g-protein, transducin, galpha subunit, membrane, receptor, gtp-binding, myristate, nucleotide-binding, g-protein-coupled receptor, rhodopsin, opsin
Biological sourceBos taurus (Bovine)
Total number of polymer chains2
Total formula weight42859.99
Scheerer, P.,Park, J.H.,Hildebrand, P.W.,Kim, Y.J.,Krauss, N.,Choe, H.-W.,Hofmann, K.P.,Ernst, O.P. (deposition date: 2008-07-09, release date: 2008-09-23, Last modification date: 2020-07-29)
Primary citationChoe, H.-W.,Ernst, O.P.,Hildebrand, P.W.,Hofmann, K.P.,Kim, Y.J.,Krauss, N.,Park, J.H.,Scheerer, P.
Crystal structure of opsin in its G-protein-interacting conformation
Nature, 455:497-502, 2008
PubMed: 18818650
DOI: 110.1038/nature07330
PDB entries with the same primary citation
Experimental method
Structure validation
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PDB entries from 2021-06-23