3DDC

Crystal Structure of NORE1A in Complex with RAS

Summary for 3DDC

Entry DOI	10.2210/pdb3ddc/pdb
Descriptor	GTPase HRas, Ras association domain-containing family protein 5, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	oncogene, tumorsuppressor, ubiquitin fold, ras effector, rap1, h-ras, rassf1, rassf5, rapl, nore1, gmppnp, adaptor, apoptosis, microtubules, hydrolase-apoptosis complex, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, anti-oncogene, cell cycle, metal-binding, microtubule, phorbol-ester binding, zinc-finger, hydrolase/apoptosis
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 Cytoplasm (By similarity): Q5EBH1
Total number of polymer chains	2
Total formula weight	37884.14
Authors	Stieglitz, B.,Bee, C.,Schwarz, D.,Yildiz, O.,Moshnikova, A.,Khokhlatchev, A.,Herrmann, C. (deposition date: 2008-06-05, release date: 2008-07-15, Last modification date: 2023-11-01)
Primary citation	Stieglitz, B.,Bee, C.,Schwarz, D.,Yildiz, O.,Moshnikova, A.,Khokhlatchev, A.,Herrmann, C. Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II Embo J., 27:1995-2005, 2008 Cited by PubMed: 18596699 DOI: 10.1038/emboj.2008.125 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation