3CIQ

A regulatable switch mediates self-association in an immunoglobulin fold

Summary for 3CIQ

• Entry DOI: 10.2210/pdb3ciq/pdb
• Related: 2f8o
• Descriptor: Beta-2-microglobulin, COPPER (II) ION, L(+)-TARTARIC ACID, ... (4 entities in total)
• Functional Keywords: class-1 mhc, amyloid, protein folding, dialysis-related amyloidosis, beta-2 microglobulin, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P61769
• Total number of polymer chains: 12
• Total formula weight: 143573.23

Authors

Calabrese, M.F.,Eakin, C.M.,Wang, J.M.,Miranker, A.D. (deposition date: 2008-03-11, release date: 2008-09-02, Last modification date: 2021-10-20)

• Primary citation: Calabrese, M.F.,Eakin, C.M.,Wang, J.M.,Miranker, A.D.; A regulatable switch mediates self-association in an immunoglobulin fold.; Nat.Struct.Mol.Biol., 15:965-971, 2008; PubMed: 19172750

Experimental method

X-RAY DIFFRACTION (2.9 Å)