3C5G

Structure of a ternary complex of the R517K Pol lambda mutant

Summary for 3C5G

• Entry DOI: 10.2210/pdb3c5g/pdb
• Related: 3C5F
• Descriptor: DNA polymerase lambda, DNA (5'-D(*DCP*DGP*DGP*DCP*DAP*DAP*DTP*DAP*DCP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*(2DT))-3'), ... (9 entities in total)
• Functional Keywords: helix-hairpin-helix, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, manganese, metal-binding, nucleotidyltransferase, nucleus, phosphoprotein, transferase, transferase/dna, lyase-dna complex, transferase-dna, lyase/dna
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q9UGP5
• Total number of polymer chains: 8
• Total formula weight: 88814.92

Authors

Garcia-Diaz, M.,Bebenek, K.,Foley, M.C.,Pedersen, L.C.,Schlick, T.,Kunkel, T.A. (deposition date: 2008-01-31, release date: 2008-07-29, Last modification date: 2021-10-20)

• Primary citation: Bebenek, K.,Garcia-Diaz, M.,Foley, M.C.,Pedersen, L.C.,Schlick, T.,Kunkel, T.A.; Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda.; Embo Rep., 9:459-464, 2008; PubMed: 18369368; DOI: 10.1038/embor.2008.33

Experimental method

X-RAY DIFFRACTION (2.2 Å)