Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0034061 | molecular_function | DNA polymerase activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0006281 | biological_process | DNA repair |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0034061 | molecular_function | DNA polymerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 602 |
| Chain | Residue |
| A | ASP427 |
| A | ASP429 |
| A | D3T576 |
| A | NA803 |
| A | HOH976 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 803 |
| Chain | Residue |
| A | MG602 |
| P | HOH671 |
| A | ASP427 |
| A | ASP429 |
| A | ASP490 |
| A | D3T576 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 804 |
| Chain | Residue |
| A | SER339 |
| A | ILE341 |
| A | ALA344 |
| P | DA5 |
| P | HOH170 |
| P | HOH311 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 805 |
| Chain | Residue |
| A | CYS300 |
| A | ILE302 |
| A | PRO303 |
| A | ILE305 |
| B | HOH953 |
| D | DC3 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO T 2801 |
| Chain | Residue |
| D | DG1 |
| D | DC2 |
| T | DG2 |
| T | DG3 |
| T | HOH619 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA P 807 |
| Chain | Residue |
| A | GLN372 |
| A | HOH866 |
| A | HOH934 |
| P | DG3 |
| P | DT4 |
| P | HOH342 |
| site_id | AC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE D3T B 577 |
| Chain | Residue |
| B | ARG386 |
| B | GLY416 |
| B | SER417 |
| B | ARG420 |
| B | GLY426 |
| B | ASP427 |
| B | ASP429 |
| B | TYR505 |
| B | PHE506 |
| B | GLY508 |
| B | ALA510 |
| B | ASN513 |
| B | MG601 |
| B | NA802 |
| B | HOH840 |
| B | HOH984 |
| B | HOH1008 |
| B | HOH1067 |
| B | HOH1098 |
| Q | 2DT6 |
| Q | HOH16 |
| U | DA5 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 601 |
| Chain | Residue |
| B | ASP427 |
| B | ASP429 |
| B | D3T577 |
| B | NA802 |
| B | HOH1067 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 801 |
| Chain | Residue |
| B | SER339 |
| B | ILE341 |
| B | ALA344 |
| Q | DA5 |
| Q | HOH7 |
| Q | HOH12 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 802 |
| Chain | Residue |
| B | ASP427 |
| B | ASP429 |
| B | ASP490 |
| B | D3T577 |
| B | MG601 |
| Q | HOH16 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 806 |
| Chain | Residue |
| A | LYS307 |
| B | CYS300 |
| B | ILE302 |
| B | ILE305 |
| E | DC3 |
| site_id | BC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE D3T A 576 |
| Chain | Residue |
| T | DA5 |
| A | ARG386 |
| A | GLY416 |
| A | SER417 |
| A | ARG420 |
| A | GLY426 |
| A | ASP427 |
| A | ASP429 |
| A | TYR505 |
| A | PHE506 |
| A | GLY508 |
| A | ALA510 |
| A | ASN513 |
| A | MG602 |
| A | NA803 |
| A | HOH976 |
| A | HOH1125 |
| A | HOH1126 |
| A | HOH1128 |
| A | HOH1129 |
| P | 2DT6 |
| P | HOH671 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 808 |
| Chain | Residue |
| B | GLU396 |
| B | GLN400 |
| B | CYS412 |
| B | HOH947 |
| B | HOH949 |
| B | HOH1076 |
Functional Information from PROSITE/UniProt
| site_id | PS00522 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_X DNA polymerase family X signature. GSYrRGkatCgDVDVLIthP |
| Chain | Residue | Details |
| A | GLY416-PRO435 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 112 |
| Details | Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"14992725","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Region: {"description":"Involved in primer binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Schiff-base intermediate with DNA","evidences":[{"source":"PubMed","id":"11457865","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17475573","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PFP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PFQ","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17475573","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2PFO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PFQ","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1jms |
| Chain | Residue | Details |
| A | ASP490 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1jms |
| Chain | Residue | Details |
| B | ASP490 | |
