3BTI

crystal structure of QacR(E58Q) bound to berberine

Summary for 3BTI

Entry DOI	10.2210/pdb3bti/pdb
Related	1jty 1jum 1jup 1rkw 3BT9 3BTC 3BTJ
Descriptor	HTH-type transcriptional regulator qacR, SULFATE ION, BERBERINE, ... (4 entities in total)
Functional Keywords	qacr, multidrug binding, berberine, natural drug, dna-binding, plasmid, repressor, transcription, transcription regulation
Biological source	Staphylococcus aureus subsp. aureus Mu50
Total number of polymer chains	4
Total formula weight	90582.06
Authors	Schumacher, M.A.,Schuman, J.T.,Brennan, R.G. (deposition date: 2007-12-28, release date: 2008-08-12, Last modification date: 2024-02-21)
Primary citation	Peters, K.M.,Schuman, J.T.,Skurray, R.A.,Brown, M.H.,Brennan, R.G.,Schumacher, M.A. QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization Biochemistry, 47:8122-8129, 2008 Cited by PubMed: 18616285 DOI: 10.1021/bi8008246 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation