3BPZ

HCN2-I 443-460 E502K in the presence of cAMP

Summary for 3BPZ

Entry DOI	10.2210/pdb3bpz/pdb
Related	1Q43
Descriptor	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
Functional Keywords	cnbd, c-linker, pacemaker, hcn, hcn2, channel, cyclic nucleotide, cap, pka, camp, ion channel, ligand, camp-binding, glycoprotein, ion transport, ionic channel, membrane, nucleotide-binding, phosphoprotein, potassium, potassium channel, potassium transport, sodium, sodium channel, sodium transport, transmembrane, transport, voltage-gated channel, transport protein
Biological source	Mus musculus (house mouse)
Cellular location	Cell membrane ; Multi-pass membrane protein : O88703
Total number of polymer chains	4
Total formula weight	95829.41
Authors	Craven, K.B.,Olivier, N.B.,Zagotta, W.N. (deposition date: 2007-12-19, release date: 2008-03-25, Last modification date: 2023-08-30)
Primary citation	Craven, K.B.,Olivier, N.B.,Zagotta, W.N. C-terminal movement during gating in cyclic nucleotide-modulated channels. J.Biol.Chem., 283:14728-14738, 2008 Cited by PubMed: 18367452 DOI: 10.1074/jbc.M710463200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation