3BPZ
HCN2-I 443-460 E502K in the presence of cAMP
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CMP A 641 |
| Chain | Residue |
| A | HOH148 |
| A | THR592 |
| A | ALA593 |
| A | ARG632 |
| A | ILE636 |
| A | HOH220 |
| A | MET572 |
| A | PHE580 |
| A | GLY581 |
| A | GLU582 |
| A | ILE583 |
| A | CYS584 |
| A | ARG591 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CMP B 641 |
| Chain | Residue |
| B | PHE580 |
| B | GLY581 |
| B | GLU582 |
| B | ILE583 |
| B | CYS584 |
| B | ARG591 |
| B | THR592 |
| B | ALA593 |
| B | ARG632 |
| B | ILE636 |
| B | HOH839 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CMP C 641 |
| Chain | Residue |
| C | MET572 |
| C | PHE580 |
| C | GLY581 |
| C | GLU582 |
| C | ILE583 |
| C | CYS584 |
| C | ARG591 |
| C | THR592 |
| C | ALA593 |
| C | ARG632 |
| C | ILE636 |
| C | HOH865 |
| C | HOH894 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CMP D 641 |
| Chain | Residue |
| D | PHE580 |
| D | GLY581 |
| D | GLU582 |
| D | ILE583 |
| D | CYS584 |
| D | ARG591 |
| D | THR592 |
| D | ALA593 |
| D | ARG632 |
| D | ILE636 |
Functional Information from PROSITE/UniProt
| site_id | PS00888 |
| Number of Residues | 17 |
| Details | CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrEGTiGKkMYFIqhG |
| Chain | Residue | Details |
| A | ILE544-GLY560 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18367452","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19525958","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3BPZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
