3BPZ
HCN2-I 443-460 E502K in the presence of cAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | polymer | 202 | 23628.1 | 4 | UniProt (O88703) Pfam (PF00027) | Mus musculus (house mouse) | Brain cyclic nucleotide-gated channel 2, BCNG-2, Hyperpolarization-activated cation channel 1, HAC-1 |
| 2 | E, F, G, H (A, B, C, D) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 4 | Chemie (CMP) PubChem (176488666) PubChem (6076) PubChem (23902375) PubChem (25322948) PubChem (40467852) PubChem (44629928) PubChem (25322946) PubChem (56973690) PubChem (216878) PubChem (59909322) PubChem (59968988) PubChem (70878457) PubChem (59350541) PubChem (3080770) PubChem (3246347) PubChem (274) PubChem (6604194) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (124132380) PubChem (12071879) PubChem (12866365) PubChem (163043517) PubChem (129317551) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (163043518) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1044 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 443 - 640 (UniProt: O88703)
| PDB | External Database | Details |
|---|---|---|
| Gly 439 | - | expression tag |
| Ser 440 | - | expression tag |
| Ala 441 | - | expression tag |
| Met 442 | - | expression tag |
| Lys 502 | Glu 502 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94512.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1316.8 | |
| All* | Total formula weight | 95829.4 |
