3BPZ
HCN2-I 443-460 E502K in the presence of cAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | polymer | 202 | 23628.1 | 4 | UniProt (O88703) Pfam (PF00027) | Mus musculus (house mouse) | Brain cyclic nucleotide-gated channel 2, BCNG-2, Hyperpolarization-activated cation channel 1, HAC-1 |
| 2 | E, F, G, H (A, B, C, D) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 4 | Chemie (CMP) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 1044 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 443 - 640 (UniProt: O88703)
| PDB | External Database | Details |
|---|---|---|
| Gly 439 | - | expression tag |
| Ser 440 | - | expression tag |
| Ala 441 | - | expression tag |
| Met 442 | - | expression tag |
| Lys 502 | Glu 502 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94512.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1316.8 | |
| All* | Total formula weight | 95829.4 |
