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3BP4

The high resolution crystal structure of HLA-B*2705 in complex with a Cathepsin A signal sequence peptide pCatA

Summary for 3BP4
Entry DOI10.2210/pdb3bp4/pdb
Related3BP7
DescriptorHLA class I histocompatibility antigen, B-27 alpha chain, Beta-2-microglobulin, nonameric peptide from Lysosomal protective protein, ... (5 entities in total)
Functional Keywordsmajor histocompatibility complex, mhc, human leukocyte antigen, hla, beta-2-microglobulin, b2m, cathepsin a, pcata, ankylosing spondylitis, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, carboxypeptidase, hydrolase, lysosome, protease, zymogen, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P03989
Secreted . Note=(Microbial infection) In the presence of M: P61769
Lysosome: P10619
Total number of polymer chains3
Total formula weight44973.90
Authors
Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Uchanska-Ziegler, B.,Ziegler, A. (deposition date: 2007-12-18, release date: 2008-12-23, Last modification date: 2023-11-01)
Primary citationKumar, P.,Vahedi-Faridi, A.,Saenger, W.,Merino, E.,Lopez de Castro, J.A.,Uchanska-Ziegler, B.,Ziegler, A.
Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284:29784-29797, 2009
Cited by
PubMed: 19617632
DOI: 10.1074/jbc.M109.038497
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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