3BP4
The high resolution crystal structure of HLA-B*2705 in complex with a Cathepsin A signal sequence peptide pCatA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, B-27 alpha chain | polymer | 276 | 31928.2 | 1 | UniProt (P03989) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) | Homo sapiens (human) | MHC class I antigen B*27, Leukocyte Antigen (HLA) B*2705 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | nonameric peptide from Lysosomal protective protein | polymer | 9 | 982.2 | 1 | UniProt (P10619) | Homo sapiens | Cathepsin A, Carboxypeptidase C, Protective protein for beta-galactosidase |
| 4 | D, E (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G, H (A, B, C) | water | water | 18.0 | 502 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44789.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 44973.9 |
