3B6T
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution
Summary for 3B6T
Entry DOI | 10.2210/pdb3b6t/pdb |
Related | 1FTJ 1FTO 1P1U 3B6Q 3B6W |
Descriptor | Glutamate receptor 2, SULFATE ION, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, ... (4 entities in total) |
Functional Keywords | glur2, t686a, mutant, quisqualate, ampa receptor, ionotropic glutamate receptor, alternative splicing, cell junction, glycoprotein, ion transport, ionic channel, lipoprotein, membrane, palmitate, phosphorylation, postsynaptic cell membrane, rna editing, synapse, transmembrane, transport, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 1 |
Total formula weight | 29476.85 |
Authors | Cho, Y.,Lolis, E.,Howe, J.R. (deposition date: 2007-10-29, release date: 2008-02-05, Last modification date: 2021-10-20) |
Primary citation | Zhang, W.,Cho, Y.,Lolis, E.,Howe, J.R. Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28:932-943, 2008 Cited by PubMed: 18216201DOI: 10.1523/JNEUROSCI.3309-07.2008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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