3B6T
Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor 2 | polymer | 263 | 29191.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2 |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID | non-polymer | 189.1 | 1 | Chemie (QUS) | |||
| 4 | D (A) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 392 - 506 (UniProt: P19491)
A: 632 - 775 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 390 | - | expression tag |
| Ala 391 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 630 | - | linker |
| Thr 631 | - | linker |
| Ala 686 | Thr 707 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29191.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 285.2 | |
| All* | Total formula weight | 29476.8 |
