3A3I

Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae, complexed with ampicillin (AIX)

Summary for 3A3I

• Entry DOI: 10.2210/pdb3a3i/pdb
• Related: 3A3D 3A3E 3A3F 3A3J
• Descriptor: Penicillin-binding protein 4, (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (3 entities in total)
• Functional Keywords: penicillin binding protein 4, pbp4, dacb, hydrolase, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Haemophilus influenzae
• Total number of polymer chains: 2
• Total formula weight: 100282.73

Authors

Kawai, F.,Roper, D.I.,Park, S.-Y.,Tame, J.R.H. (deposition date: 2009-06-12, release date: 2009-12-22, Last modification date: 2013-11-20)

• Primary citation: Kawai, F.,Clarke, T.B.,Roper, D.I.,Han, G.-J.,Hwang, K.Y.,Unzai, S.,Obayashi, E.,Park, S.-Y.,Tame, J.R.H.; Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae; J.Mol.Biol., 396:634-645, 2010; PubMed: 19958776; DOI: 10.1016/j.jmb.2009.11.055

Experimental method

X-RAY DIFFRACTION (2 Å)