3A3I
Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae, complexed with ampicillin (AIX)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000270 | biological_process | peptidoglycan metabolic process |
| A | 0004185 | molecular_function | serine-type carboxypeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0009002 | molecular_function | serine-type D-Ala-D-Ala carboxypeptidase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0042597 | cellular_component | periplasmic space |
| B | 0000270 | biological_process | peptidoglycan metabolic process |
| B | 0004185 | molecular_function | serine-type carboxypeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0009002 | molecular_function | serine-type D-Ala-D-Ala carboxypeptidase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0042597 | cellular_component | periplasmic space |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AIX A 501 |
| Chain | Residue |
| A | ALA68 |
| A | HOH550 |
| A | SER69 |
| A | PHE167 |
| A | SER310 |
| A | ASN312 |
| A | LEU362 |
| A | THR421 |
| A | GLY422 |
| A | SER423 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AIX B 501 |
| Chain | Residue |
| B | ALA68 |
| B | SER69 |
| B | PHE167 |
| B | SER310 |
| B | ASN312 |
| B | LEU362 |
| B | LYS420 |
| B | THR421 |
| B | GLY422 |
| B | SER423 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"UniProtKB","id":"P39844","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P39844","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"P39844","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
