38FY

CYP3A4 bound to vardenafil

Summary for 38FY

• Entry DOI: 10.2210/pdb38fy/pdb
• EMDB information: 78784
• Descriptor: Cytochrome P450 3A4, 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: inhibited complex, cytochrome p450, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 169004.68

Authors

Orta, A.K.,Fraser, J.S. (deposition date: 2026-08-24, release date: 2026-09-30)

• Primary citation: Orta, A.K.,Fraser, J.S.; Structural analysis of CYP3A4 inhibition by Cryo-EM; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)