38FY
CYP3A4 bound to vardenafil
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cytochrome P450 3A4 | polymer | 485 | 55555.5 | 3 | UniProt (P08684) | Homo sapiens (human) | 1,4-cineole 2-exo-monooxygenase,8-cineole 2-exo-monooxygenase,Albendazole monooxygenase (sulfoxide-forming),Albendazole sulfoxidase,CYPIIIA3,CYPIIIA4,Cholesterol 25-hydroxylase,Cytochrome P450 3A3,Cytochrome P450 HLp,Cytochrome P450 NF-25,Cytochrome P450-PCN1,Nifedipine oxidase,Quinine 3-monooxygenase |
| 2 | D (A) | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE | non-polymer | 488.6 | 1 | Chemie (VDN) | |||
| 3 | E, F, G (A, B, C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 3 | Chemie (HEM) |
Sequence modifications
A, B, C: 23 - 503 (UniProt: P08684)
| PDB | External Database | Details |
|---|---|---|
| His 504 | - | expression tag |
| His 505 | - | expression tag |
| His 506 | - | expression tag |
| His 507 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 166666.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2338.1 | |
| All* | Total formula weight | 169004.7 |
