34AK

Homo sapiens Eukaryotic translation initiation factor 4E (eIF4E) in complex with synthetic mRNA cap analogs

Summary for 34AK

• Entry DOI: 10.2210/pdb34ak/pdb
• Descriptor: Eukaryotic translation initiation factor 4E, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: complex with cap analogue, rna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 92876.79

Authors

Schneider, S.,Schwarz, A. (deposition date: 2026-09-03, release date: 2026-10-14)

• Primary citation: Schneider, S.,Moreno, S.,Thran, M.,Schwarz, A.; Structural basis of eIF4E recognition of synthetic mRNA cap analogues links cap architecture to affinity and biological activity; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)