34AK
Homo sapiens Eukaryotic translation initiation factor 4E (eIF4E) in complex with synthetic mRNA cap analogs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Eukaryotic translation initiation factor 4E | polymer | 192 | 22387.5 | 4 | UniProt (P06730) | Homo sapiens (human) | eIF-4E,eIF4E,eIF-4F 25 kDa subunit,mRNA cap-binding protein |
| 2 | E, G, I, J (A, B, C, D) | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE | non-polymer | 801.5 | 4 | Chemie (V9G) | |||
| 3 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | H (B) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 5 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 28 - 217 (UniProt: P06730)
| PDB | External Database | Details |
|---|---|---|
| Pro 26 | - | expression tag |
| Met 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89549.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3327.0 | |
| All* | Total formula weight | 92876.8 |
