32CR

SHANK3 PDZ (570-664) in complex with an internal PDZ binding motif (843-864) in Densin-180

Summary for 32CR

• Entry DOI: 10.2210/pdb32cr/pdb
• Descriptor: SH3 and multiple ankyrin repeat domains protein 3, Leucine-rich repeat-containing protein 7 (3 entities in total)
• Functional Keywords: postsynaptic density pdz domain, protein binding
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 8
• Total formula weight: 54746.45

Authors

Kallem, T.,Goult, B.T. (deposition date: 2026-07-05, release date: 2026-07-22)

• Primary citation: Otani, Y.,Srinivasan, V.,Toller, J.,Kallem, T.,Ball, N.,Barsukov, I.,Saarikangas, J.,Kreienkamp, H.J.,Goult, B.T.; An internal PDZ-binding motif in Densin-180 promotes activity-dependent SHANK scaffold remodelling; Biorxiv, 2026; DOI: 10.64898/2026.07.07.736929

Experimental method

X-RAY DIFFRACTION (1.98 Å)