31RF

POLQ-Taq chimera

Summary for 31RF

• Entry DOI: 10.2210/pdb31rf/pdb
• Descriptor: DNA polymerase I, thermostable,DNA polymerase theta, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*AP*AP*AP*AP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... (6 entities in total)
• Functional Keywords: polymerase, dna complex, dna binding protein
• Biological source: Thermus aquaticus; More
• Total number of polymer chains: 6
• Total formula weight: 138614.73

Authors

Pflug, A.,Oliveira, T.M. (deposition date: 2026-06-18, release date: 2026-11-04)

• Primary citation: Oliveira, T.M.,Pflug, A.; Discovery of a novel series of benzimidazoles/purines as potent, selective and orally active inhibitors of the DNA polymerase activity of POLQ; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.98 Å)