31EP

P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein, ADP and aluminum fluoride

Summary for 31EP

Entry DOI	10.2210/pdb31ep/pdb
EMDB information	58342
Descriptor	Lon protease homolog, mitochondrial, unknown translocated polypeptide substrate, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	aaa+ protease, lon protease, transition state, motor protein
Biological source	Homo sapiens More
Total number of polymer chains	8
Total formula weight	583764.81
Authors	Schenck, N.,Filipcik, P.,Abrahams, J.P. (deposition date: 2026-05-29, release date: 2026-06-17, Last modification date: 2026-09-02)
Primary citation	Schenck, N.,Filipcik, P.,Abrahams, J.P. Human mitochondrial Lon protease initiates unidirectional degradation from either substrate terminus Biorxiv, 2026 Cited by DOI: 10.64898/2026.05.18.725877 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.54 Å)

Structure validation