31EP
P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein, ADP and aluminum fluoride
Functional Information from PROSITE/UniProt
| site_id | PS01046 |
| Number of Residues | 9 |
| Details | LON_SER ATP-dependent serine proteases, lon family, serine active site. DGPSAGCTI |
| Chain | Residue | Details |
| A | ASP852-ILE860 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03120","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14739292","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24520911","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33431889","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03120","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 42 |
| Details | Binding site: {"description":"in chain A","evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NGF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"description":"in chain A","evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NGF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P09","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7P0M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"description":"in chain a","evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NGF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NFY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NGC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NGF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NFY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NGC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NGF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 12 |
| Details | Binding site: {"description":"in chain A","evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | Binding site: {"description":"in chain B","evidences":[{"source":"PubMed","id":"35870450","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NG4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NGF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38688959","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8OJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8OKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8OVF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38688959","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8OKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8OM7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
