30TO

14-3-3sigma protein binding to TSC2-strong peptide (RSH mutation) and stabilizer 3'deAc FC-A.

Summary for 30TO

• Entry DOI: 10.2210/pdb30to/pdb
• Descriptor: 14-3-3 protein sigma, TSC2 peptide pS1254 wt, De-acetylated Fusicoccin, ... (7 entities in total)
• Functional Keywords: 14-3-3, peptide-protein interaction, tsc2, stabilizer, peptide binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 28415.69

Authors

Pennings, M.A.M.,Brunsveld, L. (deposition date: 2026-05-13, release date: 2026-08-26)

• Primary citation: Pennings, M.A.M.,Vandenboorn, E.M.F.,Nooren, L.,Ottmann, C.,Brunsveld, L.; Mechanistic Insights into Molecular Glue Cooperativity: A 14-3-3 Case Study; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)