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30TO

14-3-3sigma protein binding to TSC2-strong peptide (RSH mutation) and stabilizer 3'deAc FC-A.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)Homo sapiens (human)Epithelial cell marker protein 1,Stratifin
2B
(B)
TSC2 peptide pS1254 wtpolymer101094.11Homo sapiens
3C
(A)
De-acetylated Fusicoccinnon-polymer638.81Chemie (SIT)
PubChem (101306709)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
PubChem (312)
5E, F
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
PubChem (271)
6G
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
7H, I
(A, B)
waterwater18.0215Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27637.0
Non-Polymers*Number of molecules5
Total formula weight778.7
All*Total formula weight28415.7
*Water molecules are not included.

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PDB entries from 2026-08-26

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