30BG

Structure of the Hepatitis C Virus E2 Core from Genotype 6a in Complex with 1-69 Germline-Reverted Variants of the Broadly Neutralizing Antibody U1

Summary for 30BG

• Entry DOI: 10.2210/pdb30bg/pdb
• Descriptor: HCV E2 envelope protein, Fab U1 1-69 heavy chain, Fab U1 1-69 light chain, ... (5 entities in total)
• Functional Keywords: hepatitis c virus, e2 envelope protein, neutralizing antibodies, germ line, viral protein
• Biological source: Recombinant Hepatitis C virus HK6a/JFH-1; More
• Total number of polymer chains: 3
• Total formula weight: 68755.95

Authors

Yechezkel, I.,Tzarum, N. (deposition date: 2026-04-19, release date: 2026-10-07)

• Primary citation: Yechezkel, I.,Maymon, H.,Tennenhouse, A.,Chen, F.,Tarabih, H.,Weisz, J.,Fraenkel, R.,Fleishman, S.J.,law, M.,Tzarum, N.; Structural and biochemical studies of the hepatitis C virus envelope proteins to promote germline-targeting vaccine design; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.31 Å)