2ZNE

Crystal structure of Zn2+-bound form of des3-23ALG-2 complexed with Alix ABS peptide

Summary for 2ZNE

Entry DOI	10.2210/pdb2zne/pdb
Related	2ZN8 2ZN9 2ZND
Descriptor	Programmed cell death protein 6, 16-meric peptide from Programmed cell death 6-interacting protein, ZINC ION, ... (5 entities in total)
Functional Keywords	penta-ef-hand protein, calcium binding protein, apoptosis, endoplasmic reticulum, membrane, nucleus, polymorphism, cytoplasm, host-virus interaction, protein transport, transport
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus membrane; Peripheral membrane protein: O75340 Cytoplasm, cytosol: Q8WUM4
Total number of polymer chains	4
Total formula weight	43867.30
Authors	Suzuki, H.,Kawasaki, M.,Inuzuka, T.,Kakiuchi, T.,Shibata, H.,Wakatsuki, S.,Maki, M. (deposition date: 2008-04-22, release date: 2008-09-09, Last modification date: 2023-11-01)
Primary citation	Suzuki, H.,Kawasaki, M.,Inuzuka, T.,Okumura, M.,Kakiuchi, T.,Shibata, H.,Wakatsuki, S.,Maki, M. Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism Structure, 16:1562-1573, 2008 Cited by PubMed: 18940611 DOI: 10.1016/j.str.2008.07.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation