2ZNE
Crystal structure of Zn2+-bound form of des3-23ALG-2 complexed with Alix ABS peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Programmed cell death protein 6 | polymer | 169 | 19877.1 | 2 | UniProt (O75340) Pfam (PF13499) | Homo sapiens (Human) | Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2 |
| 2 | C, D (C, D) | 16-meric peptide from Programmed cell death 6-interacting protein | polymer | 16 | 1771.9 | 2 | UniProt (Q8WUM4) | PDCD6-interacting protein, ALG-2-interacting protein 1, Hp95 | |
| 3 | E, F, G, H, J... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | I, N (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 191 (UniProt: O75340)
C, D: 1 - 16 (UniProt: Q8WUM4)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 3 | deletion |
| - | Tyr 4 | deletion |
| - | Ser 5 | deletion |
| - | Tyr 6 | deletion |
| - | Arg 7 | deletion |
| - | Pro 8 | deletion |
| - | Gly 9 | deletion |
| - | Pro 10 | deletion |
| - | Gly 11 | deletion |
| - | Ala 12 | deletion |
| - | Gly 13 | deletion |
| - | Pro 14 | deletion |
| - | Gly 15 | deletion |
| - | Pro 16 | deletion |
| - | Ala 17 | deletion |
| - | Ala 18 | deletion |
| - | Gly 19 | deletion |
| - | Ala 20 | deletion |
| - | Ala 21 | deletion |
| - | Leu 22 | deletion |
| - | Pro 23 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Ser 15 | Cys 813 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43298.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 569.3 | |
| All* | Total formula weight | 43867.3 |
