2ZMF

Crystal structure of the C-terminal GAF domain of human phosphodiesterase 10A

「2E4S」から置き換えられました

2ZMF の概要

• エントリーDOI: 10.2210/pdb2zmf/pdb
• 分子名称: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: gaf domain, phosphodiesterase, camp, cgmp, cgmp-binding, hydrolase, nucleotide-binding, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q9Y233
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43611.88

構造登録者

Handa, N.,Kishishita, S.,Mizohata, E.,Omori, K.,Kotera, J.,Terada, T.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2008-04-17, 公開日: 2008-04-29, 最終更新日: 2011-07-13)

• 主引用文献: Handa, N.,Mizohata, E.,Kishishita, S.,Toyama, M.,Morita, S.,Uchikubo-Kamo, T.,Akasaka, R.,Omori, K.,Kotera, J.,Terada, T.,Shirouzu, M.,Yokoyama, S.; Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP; J.Biol.Chem., 283:19657-19664, 2008; PubMed: 18477562; DOI: 10.1074/jbc.M800595200

実験手法

X-RAY DIFFRACTION (2.1 Å)