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2ZKE

Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA

Summary for 2ZKE
Entry DOI10.2210/pdb2zke/pdb
Related2ZKD 2ZKF 2ZKG
DescriptorE3 ubiquitin-protein ligase UHRF1, DNA (5'-D(*DCP*DTP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DGP*DC)-3'), DNA (5'-D(*DGP*DCP*DAP*DAP*DTP*DCP*(5CM)P*DGP*DGP*DTP*DAP*DG)-3'), ... (4 entities in total)
Functional Keywordsprotein-dna interaction, cell cycle, developmental protein, dna damage, dna repair, dna-binding, ligase, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation pathway, zinc-finger
Biological sourceMus musculus (Mouse)
More
Cellular locationNucleus: Q8VDF2
Total number of polymer chains3
Total formula weight30746.93
Authors
Arita, K.,Ariyoshi, M.,Tochio, H.,Nakamura, Y.,Shirakawa, M. (deposition date: 2008-03-19, release date: 2008-09-09, Last modification date: 2023-11-01)
Primary citationArita, K.,Ariyoshi, M.,Tochio, H.,Nakamura, Y.,Shirakawa, M.
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
Nature, 455:818-821, 2008
Cited by
PubMed: 18772891
DOI: 10.1038/nature07249
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

221051

건을2024-06-12부터공개중

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