2ZGJ
Crystal Structure of D86N-GzmM Complexed with Its Optimal Synthesized Substrate
Summary for 2ZGJ
Entry DOI | 10.2210/pdb2zgj/pdb |
Related | 2ZGC 2ZGH |
Descriptor | Granzyme M, SSGKVPLS, SULFATE ION, ... (4 entities in total) |
Functional Keywords | serine protease, synthesized peptide, cytolysis, glycoprotein, hydrolase, secreted, zymogen |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P51124 |
Total number of polymer chains | 2 |
Total formula weight | 27290.70 |
Authors | |
Primary citation | Wu, L.,Wang, L.,Hua, G.,Liu, K.,Yang, X.,Zhai, Y.,Bartlam, M.,Sun, F.,Fan, Z. Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M J.Immunol., 183:421-429, 2009 Cited by PubMed: 19542453DOI: 10.4049/jimmunol.0803088 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report