2ZGH

Crystal Structure of active granzyme M bound to its product

Summary for 2ZGH

• Entry DOI: 10.2210/pdb2zgh/pdb
• Related: 2ZGC 2ZGJ
• Descriptor: Granzyme M, SSGKVPL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: serine protease, synthesized peptide, cytolysis, glycoprotein, hydrolase, protease, secreted, zymogen
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P51124
• Total number of polymer chains: 2
• Total formula weight: 27300.67

Authors

Wu, L.F.,Wang, L.,Hua, G.Q.,Liu, K.,Zhai, Y.J.,Sun, F.,Fan, Z.S. (deposition date: 2008-01-22, release date: 2009-01-27, Last modification date: 2023-11-01)

• Primary citation: Wu, L.,Wang, L.,Hua, G.,Liu, K.,Yang, X.,Zhai, Y.,Bartlam, M.,Sun, F.,Fan, Z.; Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M; J.Immunol., 183:421-429, 2009; PubMed: 19542453; DOI: 10.4049/jimmunol.0803088

Experimental method

X-RAY DIFFRACTION (2.17 Å)