2ZFQ

Exploring thrombin S3 pocket

Summary for 2ZFQ
Related2ZDA 2ZDL 3BIU 3BIV
Related PRD IDPRD_000604
DescriptorThrombin light chain, Thrombin heavy chain, Hirudin, ... (8 entities in total)
Functional Keywordsblood coagulation/hydrolase inhibitors, acute phase, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, protease, secreted, serine protease, zymogen, protease inhibitor, serine protease inhibitor, sulfation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P09945
Total number of polymer chains3
Total formula weight36041.99
Authors
Brandt, T.,Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-01-10, release date: 2009-01-13, Last modification date: 2017-10-11)
Primary citationBaum, B.,Brandt, T.,Hangauer, D.,Heine, A.,Klebe, G.
Exploring thrombin S3 pocket
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation
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PDB entries from 2021-06-23