2ZBK

Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms

Summary for 2ZBK

Entry DOI	10.2210/pdb2zbk/pdb
Descriptor	Type II DNA topoisomerase VI subunit A, Type 2 DNA topoisomerase 6 subunit B, RADICICOL (3 entities in total)
Functional Keywords	dna topoisomerase, dna binding protein, decatenation, atpase, drug design, dna-binding, magnesium, metal-binding, atp-binding, nucleotide-binding, structural genomics, paris-sud yeast structural genomics, ysg, isomerase
Biological source	Sulfolobus shibatae (archaea) More
Total number of polymer chains	8
Total formula weight	424405.25
Authors	Graille, M.,Cladiere, L.,Durand, D.,Lecointe, F.,Forterre, P.,van Tilbeurgh, H.,Paris-Sud Yeast Structural Genomics (YSG) (deposition date: 2007-10-22, release date: 2008-02-12, Last modification date: 2023-11-01)
Primary citation	Graille, M.,Durand, D.,Lecointe, F.,Gadelle, D.,Quevillon-Cheruel, S.,Vachette, P.,Forterre, P.,van Tilbeurgh, H. Crystal Structure of an Intact Type II DNA Topoisomerase: Insights into DNA Transfer Mechanisms Structure, 16:360-370, 2008 Cited by PubMed: 18334211 DOI: 10.1016/j.str.2007.12.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.56 Å)

Structure validation