2ZA0
Crystal structure of mouse glyoxalase I complexed with methyl-gerfelin
Summary for 2ZA0
Entry DOI | 10.2210/pdb2za0/pdb |
Related | 1FRO 1QIN 1QIP |
Descriptor | Glyoxalase I, ZINC ION, methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate, ... (4 entities in total) |
Functional Keywords | lyase, lactoylglutathione lyase, glyoxalase i, methyl-gerfelin |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 42410.58 |
Authors | Okumura, H.,Kawatani, M.,Osada, H. (deposition date: 2007-09-26, release date: 2008-08-12, Last modification date: 2023-11-01) |
Primary citation | Kawatani, M.,Okumura, H.,Honda, K.,Kanoh, N.,Muroi, M.,Dohmae, N.,Takami, M.,Kitagawa, M.,Futamura, Y.,Imoto, M.,Osada, H. The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I Proc.Natl.Acad.Sci.Usa, 105:11691-11696, 2008 Cited by PubMed: 18695250DOI: 10.1073/pnas.0712239105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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