2Z66

Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61

2Z66 の概要

• エントリーDOI: 10.2210/pdb2z66/pdb
• 関連するPDBエントリー: 2Z62 2Z63 2Z64 2Z65
• 分子名称: Variable lymphocyte receptor B, Toll-like receptor 4, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: tlr4, toll-like receptor, md-2, lps, leucine-rich repeat, glycoprotein, immune response, inflammatory response, innate immunity, membrane, transmembrane, immune system
• 由来する生物種: Eptatretus burgeri (inshore hagfish, human); 詳細
• 細胞内の位置: Cell membrane ; Single- pass type I membrane protein : O00206
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 146512.37

構造登録者

Lee, J.-O.,Kim, H.M.,Park, B.S. (登録日: 2007-07-22, 公開日: 2007-09-18, 最終更新日: 2023-11-01)

• 主引用文献: Kim, H.M.,Park, B.S.,Kim, J.-I.,Kim, S.E.,Lee, J.,Oh, S.C.,Enkhbayar, P.,Matsushima, N.,Lee, H.,Yoo, O.J.,Lee, J.-O.; Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran; Cell(Cambridge,Mass.), 130:906-917, 2007; PubMed: 17803912; DOI: 10.1016/j.cell.2007.08.002

実験手法

X-RAY DIFFRACTION (1.9 Å)