2Z64

Crystal structure of mouse TLR4 and mouse MD-2 complex

2Z64 の概要

• エントリーDOI: 10.2210/pdb2z64/pdb
• 関連するPDBエントリー: 2Z62 2Z63 2Z65 2Z66
• 分子名称: Toll-like receptor 4, Lymphocyte antigen 96, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: tlr4, toll-like receptor, md-2, lps, disease mutation, glycoprotein, immune response, inflammatory response, innate immunity, leucine-rich repeat, membrane, transmembrane, secreted, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein (By similarity): Q9QUK6; Secreted, extracellular space: Q9JHF9
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 87782.21

構造登録者

Lee, J.-O.,Kim, H.M.,Park, B.S. (登録日: 2007-07-22, 公開日: 2007-09-18, 最終更新日: 2023-11-01)

• 主引用文献: Kim, H.M.,Park, B.S.,Kim, J.-I.,Kim, S.E.,Lee, J.,Oh, S.C.,Enkhbayar, P.,Matsushima, N.,Lee, H.,Yoo, O.J.,Lee, J.-O.; Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran; Cell(Cambridge,Mass.), 130:906-917, 2007; PubMed: 17803912; DOI: 10.1016/j.cell.2007.08.002

実験手法

X-RAY DIFFRACTION (2.84 Å)