2Z5X
Crystal Structure of Human Monoamine Oxidase A with Harmine
Summary for 2Z5X
Entry DOI | 10.2210/pdb2z5x/pdb |
Related | 2Z5Y |
Descriptor | Amine oxidase [flavin-containing] A, FLAVIN-ADENINE DINUCLEOTIDE, 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, ... (6 entities in total) |
Functional Keywords | human monoamine oxidase a, fad, harmine, dimethyldecylphosphine oxide, single helix trans-membrane protein, catecholamine metabolism, flavoprotein, mitochondrion, neurotransmitter degradation, oxidoreductase, transmembrane |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P21397 |
Total number of polymer chains | 1 |
Total formula weight | 59968.56 |
Authors | Son, S.Y.,Ma, J.,Yoshimura, M.,Tsukihara, T. (deposition date: 2007-07-20, release date: 2008-04-01, Last modification date: 2023-11-01) |
Primary citation | Son, S.Y.,Ma, J.,Kondou, Y.,Yoshimura, M.,Yamashita, E.,Tsukihara, T. Structure of human monoamine oxidase A at 2.2-A resolution: The control of opening the entry for substrates/inhibitors Proc.Natl.Acad.Sci.Usa, 105:5739-5744, 2008 Cited by PubMed: 18391214DOI: 10.1073/pnas.0710626105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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