2Z5S

Molecular basis for the inhibition of p53 by Mdmx

Summary for 2Z5S

Entry DOI	10.2210/pdb2z5s/pdb
Related	1ycr 2Z5T 2cr8
Descriptor	Mdm4 protein, Cellular tumor antigen p53 (3 entities in total)
Functional Keywords	mdmx, mdm4, p53, acetylation, activator, anti-oncogene, apoptosis, cell cycle, cytoplasm, disease mutation, dna-binding, endoplasmic reticulum, nucleus, phosphorylation, polymorphism, transcription regulation
Biological source	Danio rerio (zebrafish) More
Total number of polymer chains	6
Total formula weight	52408.76
Authors	Popowicz, G.M.,Czarna, A.,Rothweiler, U.,Szwagierczak, A.,Holak, T.A. (deposition date: 2007-07-17, release date: 2007-11-06, Last modification date: 2023-11-01)
Primary citation	Popowicz, G.M.,Czarna, A.,Rothweiler, U.,Szwagierczak, A.,Krajewski, M.,Weber, L.,Holak, T.A. Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle, 6:2386-2392, 2007 Cited by PubMed: 17938582 DOI: 10.4161/cc.6.19.4740 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation